Research Unit for Tropical Diseases,"Christian de Duve" Institute of Cellular Pathology and Laboratory of Biochemistry, Université Catholique de Louvain, Brussels, Belgium
Some practical examples
This course has been designed for interactive use from a computer with a web browser such as Netscape. The course will be made available on floppy disk or on CD-ROM and can also be accessed via the internet at the following URL: <http://www.icp.ucl.ac.be/~opperd/protein_course/proteins.html> .
Although this course can be studied using the floppy disk on a stand alone computer, access to mail- and file servers and to molecular biology databases is only available when the computer has a direct connection to the Internet. In that case a floppy disk is not required and the course can be started by linking to the above URL from within your web browser.
This course is meant to provide insight in the mechanisms of evolution to which proteins are subjected and how the accumulation of mutations in polypeptides may provide us with useful information about their evolutionary history and that of the organisms that contain them. I shall explain in very general terms how a biologist goes about using computer programs for sequence analysis and the inference of evolution from protein sequences. I hope this course will provide direction as to how to approach this difficult subject. The course is not only meant to be a theoretical one, but also tends to provide as much as possible examples to illustrate the topics. It contains many hyperlinks to web sites somewhere on the Internet which can be accessed for further information or for the use of software that is not directly available to the student. All of the software discussed in this course is freely available on the web and where possible indications are given as to how these can be obtained. The theoretical part is followed by a hands on practical course where each student will have the opportunity to surf the internet and get acquainted with the sequence databases, the sequence analysis tools and servers that have been made available to the community to carry out a number of the computational tasks.
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created by :Fred Opperdoes
Last updated: 28 September 1997.