Four Plasmodium species are responsible for human malaria


The four species of Plasmodium and the nature of the disease they cause.

 P.falciparum
is prevalent in all continents

  • falciparum malaria or malaria tropica
  • acute, highly dangerous disease
  • incubation time 7-12 days
  • tertian fever (48 h)
  • only one attack, no relapse
  • cure, if any, within several months

 P.vivax

  • between 37°N and 25°S
  • benign fever
  • incubation time 15 days to 9 months
  • tertian fever (48 h periodicity)
  • relapses

 P.ovale (strongly resembles P.vivax)

  • same distribution as P.vivax but only there where P.vivax is absent
  • benign fever
  • incubation time 15 days - 4 years
  • tertian fever (48 h)
  • relapses

 P.malariae

  • benign fever
  • incubation + 3 weeks
  • quartan fever (72 h periodicity)
  • longevity 3-20 years
  • relapses

P. vivax is the most extensively distributed and causes much debilitating disease. P. falciparum, which is also widely spread, results in the most severe infections and is responsible for nearly all malaria-related deaths. P. ovale which is mainly confined to Africa is less prevalent, while P. malariae, which causes the least severe but most persistent infections, also occurs widely.


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Last updated: 4 December 1997

created by :Fred Opperdoes