Drugs available for the treatment of sleeping sickness and Nagana

Treatment of the early phase of the disease is with either pentamidine in West Africa or suramin in East Africa and for the late stage of the disease with organic arsenicals (Arsobal, Melarsoprol, Mel B). The latter treatment is not without danger and may lead in 5-10% of cases to a fatal encephalopathy. There are several problems related to some if not all of these drugs.



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Last updated: 3 November 1997.

created by :Fred Opperdoes