Plant-like enzymes in trypanosomatids


This Table is a modified version of Table 1 from Hannaert et al. (2002), entitled: "Plant-like Traits associated with Metabolism of Trypanosomatid Parasites". It gives access to supplementary information on enzymes with either a clear plant or chloroplast affiliation or of typical prokaryotic nature as the result of an event of horizontal transfer. Enzyme abbreviations in the left-hand column link to general enzyme information, their catalysed reactions, the pathways to which these enzymes belong and sets of homologous enzymes. To have access to the supplementary material available for the respective enzymes discussed in the paper, click on the corresponding item "This paper" in the right-most column.

Enzyme

Function in alga

Function in tryps

Location (Plastid, or algal Cytosol)

Reference

Sedoheptulose-1,7-bisphosphatase (SBPase) and fructose-1,6-bisphosphatase (FBPase)

Calvin cycle

Gluconeogenesis

HMP?

Gluconeogenesis

P

This paper

Glucose-6-phosphate dehydrogenase (G6PDH)

HMP

HMP

C

Krepinsky et al. 2001
This paper

6-Phosphogluconolactonase (6PGL)

HMP

HMP

P

Duffieux et al. 2000
This paper

6-phosphogluconate dehydrogenase (6PGDH)

HMP

HMP

P

Krepinsky et al. 2001
This paper

Fructose-1,6-bisphosphate aldolase (ALD)

Calvin cycle

glycolysis

P

This paper

Glyceraldehydephosphate dehydrogenase (GAPDH)

Calvin cycle

glycolysis

P

This paper and Figge et al. 1999; Fast et al., 2001

Phosphoglycerate kinase (PGK)

Calvin cycle

glycolysis

P

Adje et al. 1998 and
this paper

Phosphoglycerate mutase (PGAM)

glycolysis

glycolysis

C

Chevalier et al. 2000
This paper

Alpha-hydroxyacid dehydrogenase (AHADH)

glyoxylate cycle

aromatic amino-acid metabolism

C

Cazzulo-Franke et al, 1999
This paper

Glycerol-3-phosphate dehydrogenase (G3PDH)

glycerol metabolism

glycerol metabolism

P

Kohl et al. 1996
This paper

Alternative oxidase (AOX)

respiration

respiration

mitochondrion?

This paper

Vacuolar-H+-pyrophosphatase (V-H+-PPase)

H+-pump

H+-pump

vacuole

Drozdowicz and Rea (2001)
This paper

Omega-6-fatty-acid desaturase

fatty-acid synthesis

fatty-acid synthesis

ER?

Korn and Greenblatt, 1963
This paper

Superoxide dismutase (SOD)

ROS protection

ROS protection

P

This paper

Adenylate kinase (ADK)

ATP/ADP ratio

ATP/ADP ratio

P

This paper

Acyl carrier Protein (ACP)

fatty-acid synthesis

fatty-acid synthesis

P

This paper

Abbreviations: HMP, hexose-monophosphate shunt; ER, endoplasmic reticulum; ROS, reactive oxygen species.