Cell signaling and differentiation during host-parasite interactions: the trypanosome model

Agenda


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Annoucements

 

2002 Agenda

 

A meeting involving all participants of the IAP program was held in the IBMM at Gosselies on September 4th. Talks were given by E. Pays (ULB), L. Vanhamme (ULB), D. Perez-Morga (ULB), W. Noel (VUB), S. Magez (VUB), F. Opperdoes (UCL), P. Michels, V. Hannaert (UCL), D. Nolan (TCD), J. Rubotham (TCD/ULB), M. Boshart (MBB) and J. Van Den Abbeele (ITG). General and particular discussions occurred on different aspects of the collaborative work.

 

2003 Agenda

A meeting involving all participants of the IAP/PAI program is scheduled at the ICP in Brussels on June 23rd.

The programme is as follows:

  • 11:00-11:30 Luc Vanhamme (ULB): Control of the VSG expression sites,including during the long slender to short stumpy differentiation
  • 11:30-12:00 Michael Boshart (Munich): Cyclic nucleotide dependentsignaling, including during the long slender to short stumpy differentiation
  • lunch
  • 14:00-14:30 Alain Beschin (VUB) Molecular and biological characterisation of a trypanosome immunomodulatory factor
  • 14:30-15:00 Etienne Pays (ULB): Mechanisms of lysis and resistance to lysis by human serum
  • 15:00-15:30 Cecile Felu (ULB): From resistance to human serum to control of autophagocytosis in T. gambiense
  • 15:30-16:00 Murielle Hermans (UCL): glycosome biosynthesis and degradation - role of autophagocytosis
  • 16:00-16:30 break
  • 16:30-17:00 Derek Nolan (Dublin): Characterisation of proteins involved in endocytosis
  • 17:00-17:30 Benoit Stijlemans (VUB): Evaluation of VHH camel antibodies for diagnostic and therapeutic applications in trypanosomiasis
  • 17:30-18:00 Paul Michels (UCL) Energy and carbohydrate metabolism and its compartmentation in trypanosomes. One year of PAI research in TROP - ICP/UCL
     

 

2004 Agenda

A meeting involving all participants of the IAP/PAI program was scheduled at the VUB in Brussels on October 6th.

The programme was as follows:

  • 10:00 Guy Caljon (VUB): Analyzing the immunological role of tsetse fly saliva during trypanosoiasis transmission and characterization of major saliva componets. (Collaboration with ITG)
  • 10.30 Benoit Stijlemens (VUB): Camel antibodies (nanobodies) and trypanosomiasis (collaboration with Michael Boshart)
  • 11.00 David Perez Morga (ULB): The mechanism of ApoL-1 mediated trypanolysis
  • 11.30 Baral Toya Nath (ULB): Nanobodies as targeting tools for ApoL-1 (Collaboration with ULB)
  • 12.00 Cecile Felu (ULB): Unraveling the mechanism of serum resistance in T. gambiense
    Lunch Break
  • 14.00 Murielle Herman (ICP): Degradation of glycosomes during the differentiation of T. brucei (collaboration with ULB) 
  • 14.30 Cédric Yernaux (ICP): glycosomal ABC transporters
  • 15.00 Derek Nolan (Univ. Dublin): The role of actin in endocytosis in T. brucei
  • 15.30 Géraldine Demuylder (ULB) The arginase-inducing factor of T. brucei (collaboration VUB)
  • 16.00 Alain Beschin (VUB): Role of alternative macrophages in resistance to trypanosomiasis

 

2005 Agenda

A site visit of the IAP/PAI program is scheduled for 15 November at the IBMM Gosselies, 12, rue des Profs Jeener et Brachet, 6041 Gosselies.

Programme.

10:00-10:30  Introduction and summary of main achievements: Etienne Pays (ULB)

10:30-11:30  Presentation of promising results

Sara Devaux (ULB) Trypanosome-specific RNA polymerase subunits.

Derek Nolan (TCD) New components of the endocytic pathway of T. brucei.

Benoit Vanhollebeke (ULB) The function of apolipoprotein L.

Cecile Felu (ULB) Resistance to apoL-I in T. b. gambiense.

Murielle Herman (UCL) Autophagy during the trypanosome life cycle.

Daniel Guerra (UCL) Mathemathical modelling of the metabolism of bloodstream and procyclic T. brucei.

Michael Boshart (MBB) Induction of development in T. brucei.

Alain Beschin (VUB) Characterizing interactions between African trypanosomes and host macrophages.

Jan Van Den Abbeele (ITG) Interactions of tsetse fly saliva with T. brucei and with the murine host

11:30-12:30  Questions

13:45-15:15  Discussion

13 Oct 2004


Suggestions, questions ... ==> Fred Opperdoes