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Index Created by
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updated: Apr 26, 2001
Fred
Opperdoes
4th
COST-B9 Congress on Antiprotozoal
Chemotherapy
PROGRAMME (download
programme and abstract book as PDF file,
244k)
List
of participants
(download
as PDF file)
DATE
/ TIME SUBJECT/
AUTHORS/ TITLES SUNDAY,
May 6th 15:00-18:00 Registration Poster
Mounting MONDAY,
May 7th 9:00-9:30
OPENING OF
THE MEETING Field
situation Chairpersons:
Reto Brun and Rolf Walter 9:30-10:00 J.
Jannin current
situation in the field 10:00-10:30 S. Van
Nieuvenhove Sleeping
sickness therapy: current challenges and
opportunities 10:30-11:00 Jorge Seixas,
Christian Lengeler, Jorge Atouguia, Christian
Burri Systematic
Review On Encephalopathic Syndromes During
Melarsoprol Treatment Of Human African
Trypanosomiasis: Preliminary Results 11:00-11:30 Coffee Break
and Poster Viewing I 11:30-12:00 Raya Awad El
Tayeb, Samia Amin El Karib, Suad Mohamed Sulaiman,
Omer Zaid Baraka Hiba Awad Osman chloroquine
sensitivity studies in el&emdash;rahad area,
med-west of the sudan 1999 12:00-12:30 Hiba Awad
Osman, Raya Awad Eltayeb, Saadia Ahmed Younis, Suad
Mohammed Sulaiman antimalarial
drug utilization: a study of knowledge, attitudes
and practices (kap) of sudanese mothers towards
malaria treatment in khartoum state 12:30-14:00 Lunch Genome
projects and Genetic related studies Chairpersons:
Henri Vial and Michael Duchene 14:00-14:30 Esteban
Bontempi, Carole Branche, Kimberly Edwards, Hamid
Darban, Delal Öncü, Sindy Kluge, Lena
Åslund, Ulf Pettersson, Björn
Andersson the trypanosoma
cruzi genome project 14:30-15:00 Mitchell L
Sogin evolution of
protists: what can genomics tell us about the first
eukaryotes? 15:00-15:30 Philippe
Bastin functional
genomics and target validation by rna
interference 15:30-16:00 Coffee Break
and Poster Viewing II 16:00:16:30 Intisar E El
Rayah, Khitma H El malik, Cecile Schmid, Ronald
Kaminsky characterisation
of suramin drug -resistant t.evansi 16:30-17:00 Magdalena
Radwanska, Filip Claes, Eddy Magnus, Stefan Magez,
Veerle Lejon, Etienne Pays, Philippe
Büscher novel gene
targets to diagnose human african trypanosomiasis
(hat) 18:00 Wellcome
Reception "Porto de Honra" (Padrão dos
Descobrimentos)
TUESDAY,
May 8th BASIC
SCIENCE Chairpersons:
Thomas Seebeck and Fred
Opperdoes 9:30-10:00 William N.
Hunter pterin
metabolism and antifolate drug resistance in
trypanosomatids; structure and mechanism of
pteridine reductase 10:00-10:30 Aloysius GM
Tielens, Jaap J van Hellemond mitochondria of
trypanosomes and their evolutionary relation to
hydrogenosomes and other types of
mitochondria 10:30-11:00 Michael
Boshart, Markus Engstler, Beate Fast, Friedrich
Herberg, Carsten Krumbholz, Thorsten Riek, Susanne
Schimpf , Cordula Schulte zu Sodingen , Achim
Vogt signaling
mechanisms in life cycle control of african
trypanosomes. 11:00-11:30 Coffee Break
and Poster Viewing III 11:30-12:00 Armin Schmidt,
Henning Hillebrand and R Luise
Krauth-Siegel why are
trypanosomes sensitive towards oxidative stress if
they possess an armada of antioxidant
enzymes? 12:00-12:30 Jean Christophe
Barale, Emmanuelle Roggwiller, Thierry Blisnick,
Pierrick Uzureau and Catherine Braun Breton, Chris
J. Janse and Andrew P. Waters plasmodium
serylproteases involved in merozoite release and
red blood cell invasion 12:30-14:00 Lunch Mechanisms
of drug action and resistance Chairpersons:
Louis Tielens and Arsalan Kharazmi 14:00-14:30 José M
Pérez-Victoria, F Javier
Pérez-Victoria, Adriana Parodi-Talice,
Santiago Castanys, Francisco Gamarro. strategy for
modulation of alkyl-lysophospholipids resistance in
a multidrug resistant leishmania line 14:30-15:00 Fred R.
Opperdoes, Emma Saavedra, Francis Duffieux and Paul
A.M. Michels the glycosome
and enzymes of the hexose-monophosphate
shunt 15:00-15:30 Elisabeth
Davioud-Charvet, Sandrine Delarue, Christophe Biot,
Louis Maes, Christian Sergheraert, Philippe
Grellier, Heiner Schirmer, and Katja
Becker. an antimalarial
double-drug exhibiting in vitro and in vivo
activity: an anilino-4-quinoline conjugated with a
glutathione reductase inhibitor 15:30-16:00 Coffee Break
and Poster Viewing IV 16:00-16:30 Jacob Golenser,
Abraham Domb, Talya Mordechay, Benny Leshem, Peter
Kremsner, Adrian Luty iron chelators:
correlation between effects on plasmodia and immune
functions 16:30-17:00 Leopold
Flohé, Birgit Hofmann, Hans-Jürgen
Hecht structures of
tryparedoxins as basis for rational drug
design 17:00-17:30 Ivan Hrdy, Jiri
Vasak, Jan Tachezy, Jaroslav Kulda malate
metabolizing pathways and metronidazole resistance
in trichomonads 18:00 Lisbon
Tour and Dinner
WEDNESDAY,
May 9th DRUG
TARGETS Chairpersons:
Luise Krauth-Siegel and Jaroslav
Kulda 9:30-10:00 Michael H.
Gelb, Frederick S. Buckner, Kohei Yokoyama, Wesley
C. Van Voorhis, Jeffrey Lockman, Andrew
Hamilton protein
prenylation in trypanosomatids and in plasmodium
falciparum: an ideal drug target 10:00-10:30 Burkhard
Klenke, Mhairi Stewart, Michael P. Barrett, Reto
Brun, Ian H. Gilbert evaluation of
the p2 transporter as a selective way to deliver
polyamine analogues to trypanosoma
brucei. 10:30-11:00 Thomas Seebeck,
Stefan Kunz, Roya Zoraghi, Rahel Schaub, Kewei Gong
and Tarek Shalaby cyclic amp
signalling in trypanosoma brucei: new drug targets
? 11:00-11:30 Coffee Break
and Poster Viewing V 11:30-12:00 Fernando
Hidalgo Zarco, Victor Bernier Villamor, Luis Miguel
Ruiz Pérez, Dolores González
Pacanowska. trypanosomal
deoxyuridine 5'-triphosphate nucleotidohydrolases
as potential targets for drug design 12:00-12:30 Carsten
Wrenger, Kai Lüersen, Tanja Krause, Sylke
Müller, Rolf D Walter the plasmodium
falciparum bifunctional ornithine decarboxylase,
s-adenosylmethionine decarboxylase as a target for
chemotherapy of malaria 12:30-14:00 Lunch DRUG SCREENING
AND NEW DRUGS Chairpersons:
Simon Croft / Jacques Perie 14:00-14:30 Rosa Sinai, Avi
Golan-Goldhirsh, HTS Members, Yaakov
Pollack antimalarial
activity of extracts and compounds from diverse and
unique biological sources 14:30-15:00 Karin Seifert,
Michael Duchêne, Walther H Wernsdorfer,
Herwig Kollaritsch , Gerhard Wiedermann, Thomas
Hottkowitz, Hansjörg Eibl in vitro
activity of alkylphosphocholines against entamoeba
histolytica 15:00-15:30 Ming Chen, Lin
Zhai, Søren B. Christensen, Sven Frokjaer,
Bent Steffansen, and Arsalan Kharazmi antileishmanial
activity of novel oxygenated chalcones 15:30-16:00 Coffee Break
and Poster Viewing VI 16:00-16:30 L Zhou, JE
Hall, J Zong, GM Pollack, JR Seed, JL Allen, P
Yeramian, L McChesney-Harris, JM Ndung'u, R Mdachi,
J Ngotho, R Brun, CE Stephens, M Anbazhagan, DW
Boykin and RR Tidwell absorption,
distribution and metabolism of db289, an orally
active prodrug for treatment of african
trypanosomiasis 16:30-17:00 Richard R
Tidwell, David W Boykin, Reto Brun, Simon L Croft,
James E Hall, Ramond Mdachi, J Mathu Ndung’u,
Gary M Pollack, J Richard Seed, Karl Werbovitz, and
W David Wilson Pentamidine
Type Compounds as Antitrypanosomal and
Antileishmanial Drugs. A New Look at an Old
Agent. 17:00 Closing
remarks - Farewell Scientific
| Location
| Social
| Hotels
|
Organizers
| Sc.
committee
| Registration
| Abstract
| Proceedings
| Fellowships
4th
COST-B9 Congress on
Antiprotozoemotherapy