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COST Action B22 on "Drug development for parasitic diseases"

2003-2007

COST B22 Working Group 1 and Working Group 2 meeting on June 25th, 2004


On that day the WG1 on "Drug target identification" and WG2 on "Drug target characterization and drug development" of COST Action B22, "Drug Development for Parasitic Diseases" will meet in Brussels in the ICP, "Michel de Visscher" lecture hall from 9 -17 h. In this expert meeting the various experts of COST B22 wil present their research and discuss their future plans for the COST action. The scientific part will be open to everybody interested in the subject matter. The idea is that every member of WG1 and /or WG2 who will participate, presents his or her research as far as this relates to the COST B22 activities. Presentations should not be longer than 30 min, discussion included.

Local organiser: Fred Opperdoes

Venue: ICP, "Michel de Visscher" lecture hall, Avenue Hippocrate 74, 1200 Brussels (tel. 02/7647439)


Programme and participants

Salam Al-Karadaghi (University of Lund)
Structural aspects of polyamine synthesis enzymes as drug targets

Theodora Calogeropoulou (National Hellenic Research Foundation, Athens)
Antileishmanial ring-substituted ether phospholipids

Graham Coombs (University of Glasgow)
Drug target identification, validation and characterisation at the University of Glasgow.

Michael Duchene (University of Vienna)
Targeting Entamoeba histolytica with methods of genomics and proteomics

Maria Durisova (Slovak Academy of Sciences)
New advanced modeling methods in development of new drugs and drug formulations.

Dolores Gonzales-Pacanovska (Instituto de Parasitologia y Biomedicina 'Lopez-Neyra',Granada)
Enzymes involved in sterol and pyrimidine metabolism as drug targets in parasitic protozoa

Luise Krauth-Siegel (University of Heidelberg)
Enzymes of the trypanothione redox metabolism of trypanosomes as drug target molecules

Fred Opperdoes (ICP, Brussels)
Comparison of L. major , T. brucei and T. cruzi metabolism from genomic information

Louis Tielens (University of Utrecht)
The mitochondrial metabolism in trypanosomatids

Ivor Tittawella. (University of Umea)
Mitochondrial activity in bloodstream African trypanosomes: A potential target for drugs?

Henri Vial (CNRS University Montpellier II)
Peculiarities of the phospholipid metabolism in the malaria-causing parasite Plasmodium and pharmacological implications

Rolf Walter (Bernhard Nocht Institute for Tropical Medicine, Hamburg)
Polyamine metabolism of Plasmodium falciparum as a drug target.

Dan Zilberstein (Technion - Israel Institute of Technology, Haifa)
Investigating Sb(V) mode of action in Leishmania using host-free system

Joint discussion of members of working groups 1 and 2

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